Breckenridge announces release of Duloxetine Delayed-release Capsules Breckenridge Pharmaceutical, Inc. The U.S. Esteve, S.A. Barcelona, Spain, and you will be obtainable in 20mg, 30mg and 60mg strengths. This milestone signifies the first vertically-integrated product created and commercialized between Esteve and Breckenridge.Over this right period estrogen production is taken over by the adrenal gland. If the adrenal glands are not functioning properly due to amongst other things overwork, stress, and poor diet the menopausal transition can be more traumatic. Some of the symptoms that can mark this era are: hot flashes, night sweats, dry eyes, storage loss, mood swings, melancholy, excessive menstrual bleeding, bone reduction, weight gain etc. Women usually begin to notice a change about a decade before menopause when there can be an initial minor shift in hormone levels.